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Anti-mcm6 Antibody Fab (CAT#: MOM-18434-F(P))

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human mcm6 Antibody Fab Fragment MOM-18434-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment binds selectively to Human MCM6, expressed in E. coli
  • Target
  • MCM6
  • Type
  • Fab
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for "once per cell cycle" DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
  • Function
  • ATP binding; contributes_to ATP-dependent DNA helicase activity; DNA binding; hydrolase activity; identical protein binding; nucleotide binding; protein binding; single-stranded DNA binding;
  • Synonyms
  • MCM6; minichromosome maintenance complex component 6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) , minichromosome maintenance deficient (mis5, S. pombe) 6 , minichromosome maintenance deficient 6 homolog (S. cerevisiae); DNA replication licensing factor MCM6; Mis5; MIS5 homolog (S.pombe); MIS5 homolog; minichromosome maintenance deficient 6 homolog; minichromosome maintenance deficient (mis5, S. pombe) 6; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe); P105MCM; MCG40308

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